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HelpTest Code 5AINH Factor V Inhibitor Profile, Professional Interpretation
Specimen Required
Secondary ID
607444Useful For
Interpretation of testing for factor V inhibitors
Method Name
Only orderable as a reflex. For more information see 5INHE / Factor V Inhibitor Evaluation, Plasma.
Medical Interpretation
Reporting Name
FV Inhib Profile Prof InterpSpecimen Type
Plasma Na CitSpecimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Plasma Na Cit | Frozen | 14 days |
Clinical Information
Significant bleeding can result from the presence of a coagulation factor inhibitor and could be life threatening. Whether the inhibitor is present due to hemophilia or is of an acquired nature, it greatly complicates the treatment process of a decreased factor level. The titer of the inhibitor may determine the mode of treatment. Bethesda units are a standardization to give a uniform definition of an inhibitor.
Reference Values
Only orderable as a reflex. For more information see 5INHE / Factor V Inhibitor Evaluation, Plasma.
An interpretive report will be provided.
Interpretation
When no significant abnormalities are detected, a simple descriptive interpretation is provided. When abnormal results are detected, a detailed interpretation is given, including an overview of the results and of their significance, a correlation to available clinical information, and elements of differential diagnosis.
Cautions
No significant cautionary statements
Clinical Reference
1. Biggs R, Bidwell E. A method for the study of antihemophiliac globulin inhibitors with reference to six cases. Br J Haematol. 1959;5:379-395
2. Hoyer LW: Factor VIII inhibitors. In: Hoyer LW, ed. Progress in Clinical and Biological Research. Vol 150. R Alan Liss Inc; 1984:87-98
3. Kasper CK, Aledort L, Aronson D, et al. Proceedings: A more uniform measurement of factor VIII inhibitors. Thromb Diath Haemorrh. 1975;34(2):612.
4. Kasper C, Ewing N: Acquired inhibitors of plasma coagulation factors. J Med Tech 1986;38:431-439
5. Kottke-Marchant K, ed. Laboratory Hematology Practice. Wiley Blackwell Publishing; 2012
6. Hoffman R, Benz Jr EJ, Silberstein LE, et al, eds: Hematology: Basic Principles and Practice. 7th ed. Elsevier; 2018
Method Description
A coagulation expert (clinician or hematopathologist) reviews the laboratory data, and an interpretive report is issued.
Day(s) Performed
Monday through FridayReport Available
3 to 5 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
Not ApplicableCPT Code Information
85390-26
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| 5AINH | FV Inhib Profile Prof Interp | 69049-5 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 607488 | Reviewed by | 18771-6 |
| 607444 | FV Inhib Profile Prof Interp | 69049-5 |