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General Information:

Specimen Information:

Microbiology Information:

Antibiogram Information for Saint Francis:

Regional Laboratory Requisitions:

Web Links:

Mayo Clinic Laboratories

Test Code FHPL Human Placental Lactogen (HPL)


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Specimen Type: Serum

Container/Tube: Red top

Specimen Volume: 1 mL

Collection Instructions:

1. Centrifuge at 3000 rpm for 10 minutes

2. Aliquot 1 mL of serum into a plastic vial and freeze immediately.

3. Send serum frozen.


Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)

Reporting Name

Human Placental Lactogen

Specimen Type

Serum Red

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Frozen 90 days

Reject Due To

Hemolysis Reject
Icterus Reject
Lipemia Reject

Reference Values

Males and nonpregnant Women: 0.0-0.1 mcg/mL

1st Trimester of Pregnancy: 0.2-2.1 mcg/mL

2nd Trimester of Pregnancy: 0.5-6.7 mcg/mL

3rd Trimester of Pregnancy: 4.5-12.8 mcg/mL

Day(s) Performed

Thursday

Report Available

3 to 11 days

Performing Laboratory

BioAgilytix Diagnostics

Test Classification

The performance characteristics of the listed assay was validated by BioAgilytix Diagnostics. The US FDA has not approved or cleared this test. The results of this assay can be used for clinical diagnosis without FDA approval. BioAgilytix Diagnostics is a CLIA certified, CAP accredited laboratory for performing high complexity assays such as this one.

CPT Code Information

83632

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FHPL Human Placental Lactogen 2104-8

 

Result ID Test Result Name Result LOINC Value
Z0146 Human Placental Lactogen 2104-8

Clinical Information

Human placental lactogen (hPL; chorionic somatomammotropin) is a 21,000 Da polypeptide produced during pregnancy by placental trophoblastic cells. The level of hPL in maternal serum is directly related to placental function and fetal well-being.

 

Human placental lactogen is detected about 6 weeks after conception and its concentration increases gradually to peak levels (without decreases) until about the 34th week where it remains stable for the remainder of the pregnancy. Consistently low levels throughout pregnancy or a sudden drop in serial determinations are an indication of fetal distress. After normal delivery, the hPL concentration falls rapidly to an undetectable level.

 

The hPL levels in serum of women with multiple placenta pregnancies generally exceeds that of single placenta pregnancies. This is generally noted from the 2nd trimester to delivery.