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Test Code SOFT:Z0515 Conventional Smear-Diagnostic, Varies

Additional Codes

Ordering Mnemonic Mayo Test ID
EPIC NAME: Cervical Pap Smear Diagnostic CPAPD
EPIC CODE: LAB20215  
MAYO NAME: Diagnostic Conventional PAP Smear on Slides  

 

 

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Requirements

Patient Preparation: For optimal interpretation, Papanicolaou smears should be collected near the middle of the menstrual cycle. No douching, lubricant use, or sexual intercourse for 24 hours prior to specimen collection. 

Container/Tube: Slide

Specimen Volume: Circular scrape of cervical os

Collection Instructions:

1. Specimen containers must be labeled with a minimum of 2 unique identifiers (patient's name, and medical record number or date of birth). Containers should also be labeled with specimen source, and date collected.

2. Glass slides may be labeled with a single unique identifier, but 2 identifiers are preferred. If multiple slides are submitted, each slide must have proper identification. Glass slides should be identified with the patient's name and a second patient identifier that is also on the accompanying paperwork (ie, medical record number or date of birth)

3. Fix slides immediately in 95% alcohol or treat with commercially available spray fixative.

Specimen Transport Temperature

Specimen
Type

Temperature

Time

Special Container

Varies

Ambient  (preferred)

 

SLIDE

 

Refrigerated

 

SLIDE

Reference Values

Satisfactory for evaluation. Negative for intraepithelial lesion or malignancy.

Day(s) Test Set Up

Monday through Friday

Test Classification and CPT Coding

P3000

88164

88141-CVSPC (if appropriate)

Methodology

Light Microscopy

Method Description

Papanicolaou-stained slides are microscopically examined by a cytotechnologist. Abnormal findings are reviewed and reported by a pathologist (charged separately).(Unpublished Mayo method)

Clinical Information

Squamous cell carcinoma of the cervix is believed to develop in progressive stages from normal through precancerous (dysplastic) stages, to carcinoma in situ, and eventually invasive carcinoma. This sequence is felt to develop over a matter of years in most patients. The etiology of cervical carcinoma is unknown, but the disease is believed to be related to sexual activity and possibly sexually transmitted viral infections such as human papillomavirus (HPV). Most cervical carcinomas and precancerous conditions occur in the transformation zone (squamo-columnar junction), therefore, this area needs to be sampled if optimum results are to be obtained.

Useful For

Screening for cervical carcinoma and a number of infections of the female genital tract including human papillomavirus, herpes, Candida, and Trichomonas