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HelpTest Code Soft Z0952 (Mayo FUNBL) Fungitell, BAL
Additional Codes
| Mayo Test ID | FUNBL |
| SoftLab Test ID | Z0952 |
| SoftLab & Epic Name | Fungitell, BAL |
| Epic Code | LAB2227 |
Specimen Required
Specimen Type: Bronchoalveolar lavage
Container/Tube: Sterile container
Specimen Volume: 1 to 3 mL
Collection Instructions:
1. Collect 1 to 3 mL bronchial lavage in a sterile container.
2.Ship frozen
Secondary ID
57873Method Name
Limulus Amebocyte Lysate (LAL) Pathway
Reporting Name
Fungitell, BALSpecimen Type
LavageSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Lavage | Frozen (preferred) | 30 days |
| Refrigerated | 7 days | |
| Ambient | 4 days |
Reject Due To
| Hemolysis | Reject |
| Lipemia | Reject |
| Icterus | Reject |
| Universal transport media | Reject |
Clinical Information
The Fungitell beta-D glucan assay detects (1,3)-beta-D-glucan from the following pathogens: Candida spp., Acremonium, Aspergillus spp., Coccidioides immitis, Fusarium spp., Histoplasma capsulatum, Trichosporon spp., Sporothrix schenckii, Saccharomyces cerevisiae, and Pneumocystis jiroveci.
The Fungitell beta-D glucan assay does not detect certain fungal species, such as the genus Cryptococcus, which produces very low levels of (1,3)-beta-D-glucan, nor the Zygomycetes such as Absidia, Mucor, and Rhizopus, which are not known to produce (1,3)-beta-D-glucan. Studies indicate Blastomyces dermatitidis is usually not detected due to little (1,3)-beta-D-glucan produced in the yeast phase.
Reference Values
A reference range for specimens other than serum has not been established.
Interpretation
The performance characteristics of the Fungitell assay in bronchoalveolar lavage (BAL have been determined by Eurofins Viracor; there are no established criteria for the interpretation of Fungitell results from BAL fluid. Research studies have evaluated the use of the Fungitell assay in BAL in both immunocompromised patients (1) and acute eosinophilic pneumonia.(2)
Day(s) Performed
Monday through Saturday
Report Available
3 to 6 daysPerforming Laboratory
Eurofins ViracorCPT Code Information
87449
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| FUNBL | Fungitell, BAL | Not Provided |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| FUNBL | Fungitell, BAL | Not Provided |
Clinical Reference
1. Theel ES, Jespersen DJ, Iqbal S, et al. Detection of (1, 3)-ß-D-glucan in bronchoalveolar lavage and serum samples collected from immunocompromised hosts. Mycopathologia. 2013;175(1-2):33-41. doi:10.1007/s11046-012-9579-y
2. Kawayama T, Fujiki R, Honda J, Rikimaru T, Aizawa H. High concentration of (1-->3)-beta-D-glucan in BAL fluid in patients with acute eosinophilic pneumonia. Chest. 2003;123(4):1302-1307. doi:10.1378/chest.123.4.1302